补体活化的经典和旁路途径 CLASSICAL PATHWAY Antigen-antibody Activated CIqr252 C1qr252 (CD C4 C4b2a →C4h2a3h (C3 convertase) C4 (C5 convertase) C3a C3 C3b C5→C5b→→→→C5b6789-MA0 C6 C7 C8 C9 C3a C5a C3a B C3 C35 C3bBb C3bBb3b (C3 convertase) (C5 convertase) Microbial surfaces Factor D ALTERNATIVE PATHWAY补体活化的经典和旁路途径