ABBREVIATIONs AMP adenosine monophosphate HBD hydrogen bond donor 6-APA 6-aminopenicillanic acid HPLC ATP adenosine triphosphate chromatography IND Investigational Exemption to a DAG diacylglycerol New Drug Application deoxyribonucleic acid inositol trisphospl DMSO dimethylsulfoxide intravenous epidermal growth factor MAOI monoamine oxidase inhibitor EGF-R. epidermal growth factor mRNA Messenger RNA ece New Drug Application enzyme-bound product NMR nuclear magnetic resonance ES enzyme-substrate(complex) phosphatidylinositol FDA and Drugs agend GABA y-aminobutyric acid phospholipase C good clinical practice OSAR itive structure-activity GDP sine diphosphate GL good laboratory practice RNA ribonucleic acid GMP good manufacturing practice TRNA ribosomal RNA guanosine triphosphate SAR structure-activity relationship HBA hydrogen bond acceptor RNA