12.3 Downstream processing of penicillin Spores Buffer Organic Active PH7 solvent carbon Rotating Acid vacuum filter Mycelium Inoculum Broth pH2,5 scale-up Fermentation Bulk Washing penicillin Drying Centrifugation Crystallization A schematic view of the main operations in penicillin production. 12.3 Downstream processing of penicillin