The Mechaelis-Menten Equation You need to know how this is derived E+S点S冬E+P This is the complete chemical formula for an enzyme-catalyzed(E)reaction of substrate(S)and product(P); 。 Mechaelis-Menten equation describes the relationship between reaction rate and substrate concentration.It can explain the saturation behavior in catalyzed reactions as shown in the previous slide. Mechaelis-Menten equation is derived based on the following three conditions: 1)State steady assumption, 2)Initial velocity assumption; 3)Rate law. The Mechaelis-Menten Equation You need to know how this is derived • This is the complete chemical formula for an enzyme-catalyzed (E) reaction of substrate(S) and product(P); • Mechaelis-Menten equation describes the relationship between reaction rate and substrate concentration. It can explain the saturation behavior in catalyzed reactions as shown in the previous slide. • Mechaelis-Menten equation is derived based on the following three conditions: 1) State steady assumption; 2) Initial velocity assumption; 3) Rate law. E + S ES E + P k1 K-1 k2 K-2