The basic rule for pharmacotherapy is to maximize pain relief and minimize side effects So, administration by three-step analgesic ladder, reqular administration oral or non trauma medication, personalized medication detail management, and familiar with the drugs are beneficial content of the rule Common analgesic drugs can be simply divided into non-narcotic analgesics and narcotic analgesic drugs• The basic rule for pharmacotherapy is to maximize pain relief and minimize side effects. So, administration by three-step analgesic ladder, regular administration, oral or non￾trauma medication, personalized medication, detail management, and familiar with the drugs are beneficial content of the rule. • Common analgesic drugs can be simply divided into non-narcotic analgesics and narcotic analgesic drugs