Tosylate Esters C R-0: -0- CH3 pyridine p-toluenesulfonyl chloride ROTs,a tosylate ester TsCI,"tosyl chloride" Tosylate esters(tosylates)are typically formed from alcohols with reaction with Ts-Cl and pyridine(py). Tosylate groups undergo a variety of S2 reactions. CHCH2 S2 CH2CH3 C -Ts I一C H H +:0Ts iodide CH CH tosylate ion (S)-2-butyl tosylate (R)-2-butyl iodide The tosylate is such a good leaving group because it is a stable anion. ChlI Reacns of Alcohols (landscape) Page 7Ch11 Reacns of Alcohols (landscape) Page 7 Tosylate Esters Tosylate esters (tosylates) are typically formed from alcohols with reaction with Ts-Cl and pyridine (py). Tosylate groups undergo a variety of SN2 reactions. The tosylate is such a good leaving group because it is a stable anion