b) Proteoglycans(PGs) )aggrecan is a large proteoglycan in cartilage li decorin is secreted by fibro iv)PGs have varying amounts of GAGs v) PGs are very diverse in structure and content vi) PGs and GAGs can also complex with collagen vii) secreted proteoglycans have multiple functions vii) some PGs are not secreted ix) PG/GAGs have important roles in cell-cell Image removed due to copyright considerations. See Figure 19-39 in: Alberts. Bruce, et al. Molecular Biology of the Cell. 4th ed. New York: Garland Publishing 2002 Image may be viewed online at the NIh's PubMed Bookshelf. http://www.ncbi.nlm.nihgov/entrez/query.fcgi?db=booksb) Proteoglycans (PGs) i) form large aggregates ii) aggrecan is a large proteoglycan in cartilage iii) decorin is secreted by fibroblasts iv) PGs have varying amounts of GAGs. v) PGs are very diverse in structure and content vi) PGs and GAGs can also complex with collagen vii) secreted proteoglycans have multiple functions viii) some PGs are not secreted ix) PG/GAGs have important roles in cell-cell signaling 12 Image removed due to copyright considerations. See Figure 19-39 in: Alberts, Bruce, et al. Molecular Biology of the Cell. 4th ed. New York: Garland Publishing, 2002. Image may be viewed online at the NIH's PubMed Bookshelf. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=Books