2/16/2016 Foodborne Outbreaks Foodborne Outbreaks Improper storage of contaminated Reduce the spread of Shigella foods is the second common factor Monitor patients until stool samples are contributing to outbreaks negative Other factors: Low infectious dose underlies the high -Inadequate cooking transmission rate Contaminated equipment Shigellosis may be widespread in -Food obtained from unsafe sources institutions Natural disasters that destroy sanitary waste treatment and water purification may be associated with outbreaks Prevention Methods Shigellosis Virulence Factors Exclude food handlers who have been Shigellosis is directly attributed to the diagnosed with an illness hallmarks of Shigella virulence caused by Shigella from 1.induces diarrhea operations. 2.invades intestinal epithelial cells .Exclude food handlers 3.multiply intracellularly who havp rarrhpa 4.spread from cell to cell .Wash hands!! Control the flies.2/16/2016 8 Foodborne Outbreaks • Improper storage of contaminated foods is the second common factor contributing to outbreaks • Other factors: - Inadequate cooking - Contaminated equipment - Food obtained from unsafe sources Foodborne Outbreaks • Reduce the spread of Shigella • Monitor patients until stool samples are negative • Low infectious dose underlies the high transmission rate • Shigellosis may be widespread in institutions • Natural disasters that destroy sanitary waste treatment and water purification may be associated with outbreaks Virulence Factors Shigellosis is directly attributed to the h ll k f hallmarks of Shi ll gea vi l ru ence 1. induces diarrhea 2. invades intestinal epithelial cells 3. multiply intracellularly 4. spread from cell to cell