模式识别受体识别病毒的特征模式 Cytoplasmic viral Viral protein Endosome-lysosome viral RNA recognition recognition nucleic acid recognition TLR2 TLR4 Viral genome/ AIG-I MDA-5 LR7,8 TLR9 replication products TlR3 dsrNA SSRNACPG DNA IPS-1 00 Cytoplasm B IFN and proinflammatory cytokine production Nucleus Curr Opin Immuno/ 2007, p17Curr Opin Immunol 2007, p17 模式识别受体识别病毒的特征模式