Caveolae in endocytic traffic e Caveolae are non-clathrin coated invaginations (50-100 nm)in the plasma membrane in many cell types e Caveolae are formed by self-associating caveolin molecules(making a hairpin loop)in the membrane interacting with raft lipids e To form small signalling compartments: a number of signalling proteins are anchored, such as heterotrimeric G proteins, Src-family kinases, h-ras Be involved in endocytosis and transcytosisCaveolae in endocytic traffic Caveolae are non-clathrin coated invaginations (50-100 nm) in the plasma membrane in many cell types. Caveolae are formed by self-associating caveolin molecules (making a hairpin loop) in the membrane interacting with raft lipids. To form small signalling compartments: a number of signalling proteins are anchored, such as hetrotrimeric G proteins, Src-family kinases, H-Ras. Be involved in endocytosis and transcytosis