Fig.18.14 Cascade of events by which DNA lesions cause an arrest in G, p53gene■ Stabilization p53 protein meane Gene activation Promoter p2 G0(2N0 cye cyc p53 Cdk Cdk G1(2N) Kinase activity No kinase activity -@ Absence of kinase activity blocks @ transition to S G2(4) G Arrest in G: 三。ra意号60120000 PeterJ.Russell,Genetics Copyright Pearson Education,Inc,publishing as Berjamin Cummings. Chapter 18 slide 37