transluminal renal angioplasty with stent,.PTRAS、经皮腔内激光血管成形术和经 皮腔内超声血管成形术等。PTRA后残余狭窄≥30%、跨狭窄段压力梯度≥10mmg 是PTRA后即刻失败的标准和放置肾动脉内支架的指征。此外，支架也适用于不 能控制的肾血管性高血压，进展性肾衰和复发的急性肺水肿“。 参考文献 1. Novick AC,Fergany A.Renovascular hypertension and ischemic nephropathy.In:Wein AJ,editor. Campbell-Walsh Urology.Philadelphia:Sanders Elsevier;2007 2.Thomas D,DuBose J.Vascular disorders of the kidney.In:Godman L,editor.Cecil Textbook of Medicine 22 ed.Philadelphia:SAUNDERS Elsevier:2004.p.753-60. 3.Rimmer M,Genari F).Atheroscleroic renvascular disease and progressive renal failure.Ann ntern Med.1993May 1:118(9):712- 4.Mancia G,De Backer G,DominiczakA,Cifkova R,Fagard R,Germano G,et al.2007 Guidelines for the management of arterial hypertension:The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH)and of the European Society of Cardiology (ESC).Furopea n heart iournal.2007 Ju n:28(121462-536. 支剑笙肾血管性高血压 :蒋季杰，范亚平 ,现代肾脏病学 2001.p.574 王芳，王梅，王海燕。动脉粥样硬化患者肾动脉狭窄患病率的调查。中华肾脏病杂志 2005:33:139-42. 7.中国高血压防治指南修订委员会，中国高血压防治指南 (2005年修订版).2005. 8.Textor SC.Current approaches to renovascular hypertension.Med Clin North Am.2009 May;93(3):717-32,Table of Contents. 9.Cervenka L,Horacek V,Vaneckova l,Hubacek JA,Oliverio Ml,Coffman TM,et al.Essential role of AT1A receptor in the development of 2K1C hypertension.Hypertension.2002 Nov:40(5):735-41. 10.Crowley SD.Gurley SB.Oliverio MI.Pazmino AK.Griffiths R.Flannery Pl.et al.Distinct roles for the kidney and systemic tissuesinblood pressure regulation by the renin-angiotensin system.Cin nelA3pemdleipg2achtodecrbtgrtasocateawhbodpresaureevekFnalrepom of the Working Group on Risk and High Blood Pressure.Hypertension.1985 Jul-Aug:7(4):641-51. 12.Simon N.Franklin SS,Bleifer KH.Maxwell MH.Clinical characteristics of renovascular nsi0n.Jama.1972May29:220(9:1209-18, extor SC.Renal-artery stensis.The New England journal of medicine.2001 Feb 83446431-42 14.De Bruyne B,Manoharan G,Pijls NH,Verhamme K,Madaric J,Bartunek J,et al.Assessment of renal artery stenosis severity by pressure gradient measurements.J Am Coll Cardiol.2006 Nov 7:48(9:18515 15 Lerman LO,Nath KA,Rodriguez-Porcel M,Krier JD,Schwartz RS,Napoli C,et al.Incr oxidative stress in experimental renovascular hypertension.Hypertension.2001 Feb;37(2 Part 2:541-6 16.Jung O,Schreiber JG,Geiger H,Pedrazzini T,Busse R,Brandes RP.gp91phox-containing NADPH oxidase mediates endothelial dysfunction in renovascular hypertension.Circulation.2004 Apr transluminal renal angioplasty with stent, PTRAS)、经皮腔内激光血管成形术和经 皮腔内超声血管成形术等。PTRA 后残余狭窄≥30 %、跨狭窄段压力梯度≥10 mmHg 是 PTRA 后即刻失败的标准和放置肾动脉内支架的指征。此外，支架也适用于不 能控制的肾血管性高血压,进展性肾衰和复发的急性肺水肿 54。 参考文献 1. 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Current approaches to renovascular hypertension. Med Clin North Am. 2009 May;93(3):717-32, Table of Contents. 9. Cervenka L, Horacek V, Vaneckova I, Hubacek JA, Oliverio MI, Coffman TM, et al. Essential role of AT1A receptor in the development of 2K1C hypertension. Hypertension. 2002 Nov;40(5):735-41. 10. Crowley SD, Gurley SB, Oliverio MI, Pazmino AK, Griffiths R, Flannery PJ, et al. Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system. J Clin Invest. 2005 Apr;115(4):1092-9. 11. An epidemiological approach to describing risk associated with blood pressure levels. Final report of the Working Group on Risk and High Blood Pressure. Hypertension. 1985 Jul-Aug;7(4):641-51. 12. Simon N, Franklin SS, Bleifer KH, Maxwell MH. Clinical characteristics of renovascular hypertension. Jama. 1972 May 29;220(9):1209-18. 13. Safian RD, Textor SC. Renal-artery stenosis. The New England journal of medicine. 2001 Feb 8;344(6):431-42. 14. De Bruyne B, Manoharan G, Pijls NH, Verhamme K, Madaric J, Bartunek J, et al. Assessment of renal artery stenosis severity by pressure gradient measurements. J Am Coll Cardiol. 2006 Nov 7;48(9):1851-5. 15. Lerman LO, Nath KA, Rodriguez-Porcel M, Krier JD, Schwartz RS, Napoli C, et al. Increased oxidative stress in experimental renovascular hypertension. Hypertension. 2001 Feb;37(2 Part 2):541-6. 16. Jung O, Schreiber JG, Geiger H, Pedrazzini T, Busse R, Brandes RP. gp91phox -containing NADPH oxidase mediates endothelial dysfunction in renovascular hypertension. Circulation. 2004 Apr