Q Microbe Cross-linking Adapter of membran proteins Ig by antigen Tyrosine ITAM hosphorylation events PLCY GTP/GDP exchange activation in Ras. Rac Biochemical intermediates Inositol trisphosphate s increased cytosolic Ca2+Diacylglycerol(DAG)Ras GTP, RacGTP Active Ca2+-dependent enzymes PKC enzymes ERK,JNK Transcription factors NFAT NF-KB △p C Elsevier. Abbas& Lichtman cimMunologyUpdated2e-www.studentconsult.com BCR complex-mediated signal transduction in B cellsBCR complex-mediated signal transduction in B cells