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Fungal immunomodulatory proteins 9 Hsiao,Y.M.,Huang,Y.L.,Tang,S.C.,Shieh,G.J.,Lai,J.Y., Immunomodulatory Protein,FIP-fve,from Flammulina Wang,P.H.,Ying,T.H.and Ko,J.L.(2008).Effect of A Fungal velutipes.Journal of the Formosan Medical Association 96:517- Immunomodulatory Protein From Ganoderma tsugae on Cell 524. Cycle and Interferon-Gamma Production Through Phosphatidylinositol 3-Kinase Signal Pathway.Process Ko,J.L.,Hsu,C.I.,Lin,R.H.,Kao,C.L.and Lin,J.Y.(1995). Biochemistry 43:423-430. A New Fungal Immunomodulatory Protein,FIP-fve Isolated From The Edible Mushroom,Flammulian Velutlpes and Its Hsieh,K.Y.,Hsu,C.I.,Lin,J.Y.,Tsai,C.C.and Lin,R.H. Complete Amino Acid Sequence.European Journal of (2003).Oral Administration of An Edible-Mushroom- Biochemistry 228:244-249. Derived Protein Inhibits The Development of Food-Allergic Reactions in Mice.Clinic Experimental Allergy 33:1595-602. Kong,X.H.,Sun,Y.E,Ren,Y.C.,Xi,X.W.and Yang,Z.X. (2006).Application and Research on Imunomodulatory Hsu,H.C.,Hsu,C.I.,Lin,R.H.,Kao,C.L.and Lin,J.Y. Proteins of Flammulina velutipes.Biotechnology 16:84-88. (1997).Fip-vvo,A New Fungal Immunomodulatory Protein Isolated from Volvariella volvacea.Journal of Biological Kong,X.H.,Zhang,J.C.,Zhang,PQ.,Yu,D.S.and Yang, Chemistry 323:557-565. Z.X.(2007).Expression of FIP-fve Gene in E.coli and Preliminary Study on Its Activity.Chinese Journal of Huang,J.,Zhang,L.X.,Hu,S.N.and Yu,L.(2008). Biochemical Pharmaceufic 28:304-308. Optimizing Expression of LZ-8 Protein and Primary Assaying of Its Immunomodulatory Activity.Journal of Zhejiang Li,Q.Z.,Huang,L.,Xie,M.Q.Zhou,X.W.(2009).Cloning, University (Agriculture And Life Sciences)34:7-12.(in Chinese Expression,and furification of A Fungal Immunomodulatory with English abstract). Protein from Ganoderma lucidum.The 5th International Medicinal Mushroom Conference 338-346. Jeurink,PV.,Noguera,C.L.,Savelkoul,H.F.and Wichers, H.J.(2008).Immunomodulatory Capacity of Fungal Proteins Li,Q.Z.,Wang,X.F,Chen,Y.Y.,Lin,J.and Zhou,X.W. on The Cytokine Production of Human Peripheral Blood (2010).Cytokines Expression Induced By Ganoderma sinensis Mononuclear Cells.International Immunopharmacology Fungal Immunomodulatory Protein(FIP-gsi)in Mouse Spleen 8:1124-1133 Cells.Applied Biochemistry and Biotechnology 162:1403-1413. Jeurinka,P.V.,Noguerab,C.L.,Savelkoul,H.F.and Wichers, Li,Q.Z.,Wang,X.F.and Zhou,X.W.(2011).Recent Status H.J.(2008).Immunomodulatory Capacity of Fungal Proteins and Prospects of the Fungal Immunomodulatory Protein on The Cytokine Production of Human Peripheral Blood Family.Critical Reviews in Biotechnology (in press) Mononuclear Cells.International Immunopharmacology doi:10.3109/07388551.2010.543967. 8:1124-1133 Li Q.Z.(2010)Cloning,Optimization,and Functional Jin,M.,Jung,H.J.,Choi,J.J.,Jeon,H.,Oh,J.H.,Kim,B., Characterization of Fungi Immunomodulatory Protein and Shin,S.S.,Lee,J.K.,Yoon,K.and Kim,S.(2003).Activation Preparation of Its Polyclonal Antibody.Dissertation,Shanghai of Selective Transcription Factors and Cytokines by Jiao Tong University.Shanghai,China. Watersoluble Extract From Lentinus lepideus.Experimental Biology and Medicine (Maywood)228:749-758. Li,S.L.,Hu,Y.P.,Su,J.C.,Song,J.,Guo,Y.W.and Qi,Z.G. (2009).Cloning and Expression of LZ-8 Gene from Jinn,T.R.,Wu,C.M.,Tu,W.C.,Ko,J.L.andTzen,J.T.(2006). Ganoderma lucidum,An Immunomodulatory Protein.Journal Functional Expression of FIP-gts,A Fungal of Hebei Normal University Natural Science Edition 33:677- Immunomodulatory Protein From Ganoderma Tsugae in Sf21 681.(In Chinese with English abstract). Insect Cells.Bioscience Biotechnology and Biochemistry 70:2627-2634 Liao,C.H.,Hsiao,Y.M.,Lin,C.H.,Yeh,C.S.,Wang J.C., Ni,C.H.,Hsu,C.P.and Ko,J.L.(2008).Induction of Kino,K.,Yamashita,A.,Yamaoka,K.,Watanabe,J.,Tanaka, Premature Senescence in Human Lung Cancer By Fungal S.,Ko,K.,Shimizu,K.and Tsunoo,H.(1989).Isolated and Immunomodulatory Protein from Ganoderma tsugae.Food and Characterization of A New Immunomodulatory Protein Ling Chemical Toxicology 46:1851-1859. Zhi-8 (LZ-8),From Ganoderma Lucidum.The Journal of Biological Chemistry 264:472-478. Liao,C.H.,Hsiao,Y.M.,Hsu,C.P,Lin,M.Y.,Wang,J.C. Huang,Y.L.and Ko,J.L.(2006).Transcriptionally Mediated Ko,J.L.,Lin,S.J.,Hsu,C.I.,Kao,C.L.and Lin,J.Y.(1997). Inhibition of Telomerase of Fungal Immunomodulatory Molecular Cloning and Expression of A Fungal Protein from Ganoderma tsugae in A549 Human LungFungal immunomodulatory proteins 9 Hsiao, Y.M., Huang, Y.L., Tang, S.C., Shieh, G.J., Lai, J.Y., Wang, P.H., Ying, T.H. and Ko, J.L. (2008). Effect of A Fungal Immunomodulatory Protein From Ganoderma tsugae on Cell Cycle and Interferon-Gamma Production Through Phosphatidylinositol 3-Kinase Signal Pathway. Process Biochemistry 43:423-430. Hsieh, K.Y., Hsu, C.I., Lin, J.Y., Tsai, C.C. and Lin, R.H. (2003). Oral Administration of An Edible-Mushroom￾Derived Protein Inhibits The Development of Food-Allergic Reactions in Mice. Clinic Experimental Allergy 33:1595-602. Hsu, H.C., Hsu, C.I., Lin, R.H., Kao, C.L. and Lin, J.Y. (1997). Fip-vvo, A New Fungal Immunomodulatory Protein Isolated from Volvariella volvacea. Journal of Biological Chemistry 323:557-565. Huang, J., Zhang, L. X., Hu, S. N. and Yu, L. (2008). Optimizing Expression of LZ-8 Protein and Primary Assaying of Its Immunomodulatory Activity. Journal of Zhejiang University (Agriculture And Life Sciences) 34:7-12. (in Chinese with English abstract). Jeurink, P.V., Noguera, C.L., Savelkoul, H.F. and Wichers, H.J. (2008). Immunomodulatory Capacity of Fungal Proteins on The Cytokine Production of Human Peripheral Blood Mononuclear Cells. International Immunopharmacology 8:1124-1133. Jeurinka, P.V., Noguerab, C.L., Savelkoul, H.F. and Wichers, H.J. (2008). Immunomodulatory Capacity of Fungal Proteins on The Cytokine Production of Human Peripheral Blood Mononuclear Cells. International Immunopharmacology 8:1124-1133. Jin, M., Jung, H.J., Choi, J.J., Jeon, H., Oh, J.H., Kim, B., Shin, S.S., Lee, J.K., Yoon, K. and Kim, S. (2003). Activation of Selective Transcription Factors and Cytokines by Watersoluble Extract From Lentinus lepideus. Experimental Biology and Medicine (Maywood) 228:749-758. Jinn, T.R., Wu, C.M., Tu, W.C., Ko, J.L. and Tzen, J.T. (2006). Functional Expression of FIP-gts, A Fungal Immunomodulatory Protein From Ganoderma Tsugae in Sf21 Insect Cells. Bioscience Biotechnology and Biochemistry 70:2627-2634. Kino, K., Yamashita, A., Yamaoka, K., Watanabe, J., Tanaka, S., Ko, K., Shimizu, K. and Tsunoo, H. (1989). Isolated and Characterization of A New Immunomodulatory Protein Ling Zhi-8 (LZ-8), From Ganoderma Lucidum. The Journal of Biological Chemistry 264:472-478. Ko, J.L., Lin, S.J., Hsu, C.I., Kao, C.L. and Lin, J.Y. (1997). Molecular Cloning and Expression of A Fungal Immunomodulatory Protein, FIP-fve, from Flammulina velutipes. Journal of the Formosan Medical Association 96:517- 524. Ko, J.L., Hsu, C.I., Lin, R.H., Kao, C.L. and Lin, J.Y. (1995). A New Fungal Immunomodulatory Protein, FIP-fve Isolated From The Edible Mushroom, Flammulian Velutlpes and Its Complete Amino Acid Sequence. European Journal of Biochemistry 228:244-249. Kong, X.H., Sun, Y.F., Ren, Y.C., Xi, X.W. and Yang, Z.X. (2006). Application and Research on Imunomodulatory Proteins of Flammulina velutipes. Biotechnology 16:84-88. Kong, X.H., Zhang, J.C., Zhang, P.Q., Yu, D.S. and Yang, Z.X. (2007). Expression of FIP-fve Gene in E.coli and Preliminary Study on Its Activity. Chinese Journal of Biochemical Pharmaceufic 28:304-308. Li, Q. Z., Huang, L., Xie, M.Q. Zhou, X.W. (2009). Cloning, Expression, and furification of A Fungal Immunomodulatory Protein from Ganoderma lucidum. The 5th International Medicinal Mushroom Conference 338-346. Li, Q.Z., Wang, X.F., Chen, Y.Y., Lin, J. and Zhou, X.W. (2010). Cytokines Expression Induced By Ganoderma sinensis Fungal Immunomodulatory Protein (FIP-gsi) in Mouse Spleen Cells. Applied Biochemistry and Biotechnology 162:1403-1413. Li, Q.Z., Wang, X.F. and Zhou, X.W. (2011). Recent Status and Prospects of the Fungal Immunomodulatory Protein Family. Critical Reviews in Biotechnology (in press) doi:10.3109/07388551.2010.543967. Li Q.Z. (2010) Cloning, Optimization, and Functional Characterization of Fungi Immunomodulatory Protein and Preparation of Its Polyclonal Antibody. Dissertation, Shanghai Jiao Tong University. Shanghai, China. Li, S.L., Hu, Y.P., Su, J. C., Song, J., Guo, Y.W. and Qi, Z.G. (2009). Cloning and Expression of LZ-8 Gene from Ganoderma lucidum, An Immunomodulatory Protein. Journal of Hebei Normal University Natural Science Edition 33:677- 681. (In Chinese with English abstract). Liao, C.H., Hsiao, Y.M., Lin, C.H., Yeh, C.S., Wang J.C., Ni, C.H., Hsu, C.P. and Ko, J.L. (2008). Induction of Premature Senescence in Human Lung Cancer By Fungal Immunomodulatory Protein from Ganoderma tsugae. Food and Chemical Toxicology 46:1851-1859. Liao, C.H., Hsiao, Y.M., Hsu, C.P., Lin, M.Y., Wang, J.C., Huang, Y.L. and Ko, J.L. (2006). Transcriptionally Mediated Inhibition of Telomerase of Fungal Immunomodulatory Protein from Ganoderma tsugae in A549 Human Lung
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