1.Rank the following carboxylic acid derivatives in order of decreasing reactivity toward hydrolysis(most reactive on left): 88 8 OCH3 HaC NH2 CI A B D A)D>B>A>C D)A>B>D>C B)C>A>B>D E)D>B>C>A C)B>D>A>C Ans:A Br2 8 CH3-NH hc-88 B) HgC-N=C=O n2- E) e8-Ne Ans:CPage 1 1. Rank the following carboxylic acid derivatives in order of decreasing reactivity toward hydrolysis (most reactive on left): H3C C O H3C Cl C O OCH3 H3C C O H3C NH2 C O O CH3 C O A B CD A) D > B > A > C D) A > B > D > C B) C > A > B > D E) D > B > C > A C) B > D > A > C Ans: A 2. Which of the following is not an intermediate in the Hofmann rearrangement of ethanamide to methylamine? H3C C O NH2 CH3 NH2 Br2 NaOH H2O A) H3C C O NH - B) H3CN O C C) H2C C O NH2 - D) O H OH H3C N C E) H3C C O NHBr Ans: C