Strength of integrin bonds to ECM ligands nages removed due to copyright cons See Figure 1A and 2 in Lehenkari, P, and M. Horton Single Integrin Molecule Adhesion Forces in Intact Cells Measured by Atomic Force Microscopy Biochem Biophys Res Commun. 1999 Jun 16: 259(3): 645-50 AFM used to measure the strength of integrin bonds to various RGD ligands Single bond forces were 32-97 pr Lower forces(- 10 pn or less? )are likely adequate to produce conformational changes Lehenkari horton BbRC. 1999Strength of integrin bonds to ECM ligands� Images removed due to copyright considerations. See Figure 1A and 2 in Lehenkari, P., and M. Horton. "Single Integrin Molecule Adhesion Forces in Intact Cells Measured by Atomic Force Microscopy." Biochem Biophys Res Commun. 1999 Jun 16;259(3):645-50 AFM used to measure the strength of integrin bonds to various RGD ligands. Single bond forces were 32-97 pN. Lower forces (~ 10 pN or less?) are likely adequate to produce conformational changes. Lehenkari & Horton, BBRC, 1999