d [m R12+k12[M1刂][M2]-k21[M2刂[M1]-R1-R2=0 R1=R12+Rt生成[M1]的速率等于其消失速率 21 [M2][M1]=k12[M1[M2 k21[M2[M1] 12Lv2 d[M1]k1M1J[M1]+k21[M2[M1 代入式 k12[M1[M2]+k22[M2][M2 化简 d[M1][M1]k1/k12[M1]+[M2] dM2]M2】M+k2/k21[代入式 化简 d [M2 •] = Ri2 + k12[M1 •] [M2 ]-k2 1 [M2 •] [M1 ] -R t21-R t22 = 0 d t Ri1 = R t12 + R t11 生成[M1 •]的速率等于其消失速率 k21[M2 •] [M1 ] = k12 [M1 •] [M2 ] [M1 •] = k21[M2 •] [M1 ] k12 [M2 ] d [M1 ] d [M2 ] = k11 [M1 •] [M1 ] + k21 [M2 •] [M1 ] k12 [M1 •] [M2 ] + k22 [M2 •] [M2 ] = [M1 ] [M2 ] • k11 / k12 [M1 ] + [M2 ] [M1 ] + k22 / k21 [M2 ] d [M1 ] d [M2 ]