Common features of acute leukemias ■ Clinical features 3. Bone pain and tenderness 4. Generalized lymphadenopathy splenomegaly, and hepatomegaly More common in alL 5. Central nervous system manifestations Headache, vomiting, and nerve palsies children adults ALL>AML◼ Clinical features 3. Bone pain and tenderness 4. Generalized lymphadenopathy splenomegaly, and hepatomegaly More common in ALL 5.Central nervous system manifestations Headache, vomiting, and nerve palsies children ＞adults, ALL＞AML Common features of acute leukemias