Adhesion complexes Junction tvpe Function Extracellular or ntracellular adjacent cell attachment attachment Adherens structural, cell-cell or cell- ECM proteins or actin filaments matrix djacent cell structural. cell-cell cadherin intermediate filaments Hemidesmosome structural cell-matrix basal lamina via intermediate ntegrins filaments Focal adhesions structural cell-matrix ECM proteins actin filaments Tight j ulate transport between cells and along cell Gap junctions cell-cell communication channels formed by connexin via ion and small molecule subun its Table 2. Adhe sion complexesAdhesion complexes Junction type Function Extracellular or adjacent cell attachment Intracellular attachment Adherens structural, cell-cell or cell￾matrix ECM proteins or cadherins in actin filaments Desmosome structural, cell-cell adjacent cell cadherin intermediate filaments Hemidesmosome structural, cell-matrix basal lamina via intermediate Focal adhesions Tight junction structural, cell-matrix regulate transport between cells and along cell membrane integrins ECM proteins via integrins filaments actin filaments Gap junctions cell-cell communication via ion and small molecule chann els formed by connex in subun its exchange Table 2. Adhe sion co mplexes