Foveal schisis Bilateral foveal schisis is the most common clinical finding in patients with XLRS (68%0-100%o Folds radiate outward in a stellate pattern from the foveola, and contain microcystic schisis cavities In older individuals, RPE atrophy and gross pigment clumping may also develop, and the overall clinical picture may resemble atrophic age-related macular degeneration(AMD)Foveal schisis ◼ Bilateral foveal schisis is the most common clinical finding in patients with XLRS.(68%-100%) ◼ Folds radiate outward in a stellate pattern from the foveola, and contain microcystic schisis cavities. ◼ In older individuals, RPE atrophy and gross pigment clumping may also develop, and the overall clinical picture may resemble atrophic age-related macular degeneration (AMD)