Formation of Secondary Alcohols Reaction of an aldehyde with a Grignard reagent generates a secondary alcohol. H.C. CH, HO* CH,CH2一MgBr+ C=0 CH2一CH, -O MgBr CHCH2- OH ether H H acetaldehyde butan-2-ol (85%) Formation of Tertiary Alcohols CH.CH2CH2 CH.CH,CH2 (1)ether solvent CHCH2一MgBr+ C=0 C-OH (2)H,O CH,CH2一 HC CH pentan-2-one 3-methylhexan-3-o1 (90%) 2013 Pearon Edueon Ine This can be achieved by reaction of a Grignard with a ketone Chl0 Alcohols:Struct +synth (landscape) Page 13 Ch10 Alcohols; Struct + synth (landscape) Page 13 Formation of Secondary Alcohols Reaction of an aldehyde with a Grignard reagent generates a secondary alcohol. Formation of Tertiary Alcohols This can be achieved by reaction of a Grignard with a ketone