Organophosphates and carbamate insecticides inhibit cholinesterase Over-exposure may decrease available cholinesterase nerve enzyme Cholinesterase is the nernous system“off switch”.If inhibited, nerves continuously fire Over-stimulating muscles,glands, and organsOrganophosphates and carbamate insecticides inhibit cholinesterase ❖ Over-exposure may decrease available cholinesterase nerve enzyme ❖ Cholinesterase is the nernous system “off switch”. If inhibited, nerves continuously fire ❖ Over-stimulating muscles, glands, and organs