药物的体内过程 Genes PK Drug ◆ Absorption PK◆ Distribution ◆ Metabolisn Genotype ◆ Excretion variance ◆ Target PD◆ Mechanism ◆ Response Genes PD Outcome ◆ Efficacy ◆ ToxicityGenes PK Genes PD Genotype variance Absorption Distribution Metabolism Excretion PK Target Mechanism Response PD Efficacy Toxicity Outcome Drug 药物的体内过程