Ca2+ Calmodulin Ca2+-calmodulin Inactive myosin kinase Active myosin kinase ATP- ADP Inactive myosin Phosphorylated myosin 2001 BrockuCole-Thomson Leaming (can bind with actin) Release of Bind Ca2+into calmodulin(protein) the muscle cell Activate myosin ContractionRelease of Ca2+ into the muscle cell Bind calmodulin(protein) Activate myosin Contraction