1/26/2016 Microbial Diseases of the Lower Structures of the lower respiratory system Respiratory System Bronchiole Branch from Caused by many of the same bacteria () Brinch from the and viruses as the upper respiratory (vpice box Left lung system Trache As the bronchi become involved -Bronchitis -Bronchiolitis -Pneumonia Pulmonary alveoli are involved Bacterial Diseases of the Lower Pertussis(Whooping Cough) Respiratory System Caused by Bordetella pertussis Learning Objectives -Gram-negative coccobacillus List the causative agent,symptoms. ·Produces a capsule prevention,preferred treatment,and -Allows attachment to ciliated cells in the laboratory identification tests for trachea pertussis and tuberculosis. Destroys ciliated cells and shuts down the Compare and contrast the seven bacterial ciliary escalator pneumonias discussed in this chapter. Tracheal cytotoxin of cell wall damages List the etiology,method of transmission, ciliated cells;escalator does not work and symptoms of melioidosis. Pertussis toxin enters the bloodstream associated with systemic symptoms 51/26/2016 5 Microbial Diseases of the Lower Respiratory System • Caused by many of the same bacteria and i th i t d viruses as th e upper respira tory system • As the bronchi become involved – Bronchitis – Bronchiolitis – Pneumonia • Pulmonary alveoli are involved Structures of the lower respiratory system Pharynx (throat) Larynx ( b) Bronchiole Branch from the pulmonary vein Branch from the pulmonary artery Blood (voice box) Trachea (windpipe) Right lung Bronchus Bronchiole Pleura Left lung H t Blood capillaries Alveoli Pleura Diaphragm (breathing muscle) Heart Bacterial Diseases of the Lower Respiratory System Learning Objectives List the causative agent, symptoms, prevention, preferred treatment, and laboratory identification tests for pertussis and tuberculosis. Compare and contrast the seven bacterial pneumoni di d i hi h ias discussed i n thi s c hapter. List the etiology, method of transmission, and symptoms of melioidosis. Pertussis (Whooping Cough) • Caused by Bordetella pertussis – Gram-negative coccobacillus • Produces a capsule – Allows attachment to ciliated cells in the trachea • Destroys ciliated cells and shuts down the ciliary escalator • Tracheal cytotoxin of cell wall damages ciliated cells; escalator does not work • Pertussis toxin enters the bloodstream associated with systemic symptoms