Steady-state drug concentration 16 16 Dose -10 mg/min 826 Dose=5 mg/min 2345 6 1 23466 Time (hours) Time (hours) Continuous(multiple)dose kinetics 一Intravenous indusion Single dose Multiple doses 24 34 Time (houts) Time (nours)Steady‐state drug concentration Continuous (multiple) dose kinetics