革山院 Definition Chronic kidney disease(CKd) A spectrum of different pathophysiologic processes associated with abnormal kidney function and a progressive decline in GFR A spectrum of clinical problems beginning with abnormalities detectable only by laboratory testing to a late stage, labeled uremiaDefinition • Chronic kidney disease (CKD) – A spectrum of different pathophysiologic processes associated with abnormal kidney function and a progressive decline in GFR – A spectrum of clinical problems beginning with abnormalities detectable only by laboratory testing to a late stage, labeled uremia