七、电子传递与ATP合成的偶联机制( The chemiosmotic model was proposed to explain the coupling of electron flow and ATP synthesis) x First proposed in 1961 by Peter Michell(a British) x Energy released from electron transferring is hypothesized to be first used to pump protons from the mitochondrial matrix to the intermembrane space (or from stroma to thylakoid lumen in chloroplasts), thus generating a proton gradient across the inner membrane; such a proton-motive force then drives ATP synthesis by moving protons back into the matrix via the atP synthase-- The chemiosmotic model. x The model was initially opposed by virtually all researchers working in oxidative phosphorylation and photosynthesis七、电子传递与ATP合成的偶联机制（The chemiosmotic model was proposed to explain the coupling of electron flow and ATP synthesis） •★First proposed in 1961 by Peter Michell (a British). •★ Energy released from electron transferring is hypothesized to be first used to pump protons from the mitochondrial matrix to the intermembrane space (or from stroma to thylakoid lumen in chloroplasts), thus generating a proton gradient across the inner membrane; such a proton-motive force then drives ATP synthesis by moving protons back into the matrix via the ATP synthase-- The chemiosmotic model. •★ The model was initially opposed by virtually all researchers working in oxidative phosphorylation and photosynthesis