DYsfunction of glomerule 20% of CI Renal blood flowV Effective filtration pressure of the glomerule v Kf(LPxA, permeability and total filtration area)\ GFR↓→ Alteration of urinary quantity 125ml/min Permeability↑ (of glomerular filtration membrane Abnormality of urinary quality To urine (hematuria proteinuria) 1.5L/day 1010 Renal blood flow Effective filtration pressure of the glomerule  Kf (LPA, permeability and total filtration area)  125ml/min 180L/day 1.5L/day 99% 20% of CI Abnormality of urinary quality Alteration of urinary quantity (l) Dysfunction of glomerule Permeability  (of glomerular filtration membrane) GFR  (hematuria & proteinuria)