4、 Epidemiology 350.000.000 carriers worldwide 120.000.000 carriers in China the carrier rate can exceed 10% 15 to 25% of chronically infected patients will die from chronic liver disease 500,000 deaths/year in China 982.297 liver disease in China 2005 50% of children born to mothers with chronic HBV in the us are Asian American4、Epidemiology • 350,000,000 carriers worldwide • 120,000,000 carriers in China - the carrier rate can exceed 10% -15 to 25% of chronically infected patients will die from chronic liver disease • 500,000 deaths/year in China • 982,297 liver disease in China 2005 • 50% of children born to mothers with chronic HBV in the US are Asian American