Plasmids Replication: Most plasmids of gram-positive bacteria replicate by a rolling circle mechanism Copy number: The number of plasmids in a cell, can range from only 1-3 copies to 100 copies. Incompatibility: Two different types of Plasmids can not coexist in a cell pl Episomes: Plasmids having the ability to integrate into host chromosomePlasmids • Replication: Most plasmids of gram-positive bacteria replicate by a rolling circle mechanism. • Copy number: The number of plasmids in a cell, can range from only 1-3 copies to 100 copies. • Incompatibility: Two different types of plasmids can not coexist in a cell. • Episomes: Plasmids having the ability to integrate into host chromosome