Cholestatic Jaundice(1) Etiology and mechanism 1. Extra-hepatic obstuctive cholestasis Intra-hepatic biliary obstruction: cholelithiasis, carcinoma of bile duct Extra-hepatic biliary obstruction: cancer of the head of the pancreas, carcinoma of ampulla 2. Intra-hepatic obstructive cholestasis Intra-hepatic muddy stone Clonorchis sinesis disease Bile duct obstructed-cholanjiectasis-rupture of bile duct-bile retroflows to the blood-conjugated bilirubin IncreasedCholestatic Jaundice (1) Etiology and Mechanism 1. Extra-hepatic obstuctive cholestasis: Intra-hepatic biliary obstruction: cholelithiasis, carcinoma of bile duct Extra-hepatic biliary obstruction: cancer of the head of the pancreas, carcinoma of ampulla 2. Intra-hepatic obstructive cholestasis: Intra-hepatic muddy stone, Clonorchis sinesis disease Bile duct obstructed→cholanjiectasis→rupture of bile duct→bile retroflows to the blood→conjugated bilirubin increased