Cell Signaling General Principles of Cell Signaling 三、 Signaling mediated by Intracellular Receptors Signaling Mediated by Cell-Surface Receptors 1.lon-Channel-Linked ReceptorsCell Signaling 一、General Principles of Cell Signaling 二、Signaling Mediated by Intracellular Receptors 三、Signaling Mediated by Cell-Surface Receptors 1. Ion-Channel-Linked Receptors