Prolia,Xgeva Amge 612010 ully huma RANKI 125120 /10201 GD 12551 3282017 fully human 761055 5/12017 fully heman PD-LI 61069 3y162007 2516 113020151 humanized 76103 8272015 fully haman PCSK9 1255 4242009 fully hama 2528 7/12013 TNF 125433 219202 2501 6 10y162015 6102 421201 TNE 452D16 chimeric,biosimilar TNF Bris-Myers 32520 CTLA-4 Eli Lilly 3222016 IL17A 1142015 ILS 232D04 1242015 EGER 122220144 PD- 12555 6 pdivo 342D15 PD-1 182016 halational anthra 12550 12540