2. The mechanisms of nsaids CyclooxygenaseCOX-1 COX-2 COOH PGG2 OOH PeroxidaseCOX-1 COX-2 ∠coOH COOH OH PGH (prostacyclin) ( thromboxane) COOH OH PGD OH PGE2 15 deoxy-△12 PGJ2. The mechanisms of NSAIDs