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中国科学院 苏州生物医学工程技术研究所人事教育处 《人才快讯》2012年第三期 “海外人才走进科学院活动周”同时启动,来自美国、德国、英国、法国、澳大利亚、日 本等国家的46位获国家优秀自费留学生奖学金的海外人才代表应邀访问中国科学院,并与 国内优秀青年人才进行了交流座谈 中科院副院长詹文龙介绍,海外人才走进科学院活动周”旨在通过邀请海外优秀青年科 技人才集中访问中科院的有关研究所并进行学术交流,与海外人才建立起交流密切的联络机 制,向海外人才宣传国家和院的人才政策与举措,搭建长期合作与双向选择的平台。 中科院人才发展主题活动日上还举行了中国科学院“海外评审专家”聘请仪式。一批优秀人才 分别获得中科院青年科学家奖、卢嘉锡青年人才奖、中科院技术能手荣誉称号。 高校动态 清华大学学术报告一: In situ self- assembly of highly potent, biodegradable, radionuclide seeds for brachy therapy 时间:6月13日下午3:30 地点:清华大学医学科学楼B321 报告人: Wenge liu,PhD.( Associate Research Professor, Duke University) 报告摘要 Intratumoral administration of radionuclides(radionuclide therapy) has the potential to deliver the maximum amount of radioactivity to the tumor and can spare surrounding tissues from harmful side effects. All the radionuclides, however, are unable to capitalize on this effect because they are rapidly cleared from the tumor following injection due to their low molecular weight. Elastin-like polypeptides(ELP)are a class of genetically engineered polymers that undergo an inverse temperature phase transition; they are soluble at the temperatures below their characteristic transition temperature(Tt), and form insoluble aggregates above their Tt. Using this ELP, we developed a versatile, genetically engineered peptide polymer as a"smart"radionuclide carrier that displays potent antitumor efficacy by rationally tailoring intratumoral retention time through the modulation of its phase transition behavior. The therapeutic efficacy herein reported, which led to 100% response rates in two human tumor xenograft models and greater than 67% of complete tumor regression until the completion of the experiment (i.e, 60 days), is in stark contrast with the efficacy observed on our seminal work with radiolabeled ELPs. This radiotherapy modality howed very minimal systemic toxicity in mice. These data indicate the in situ self-assembly of biodegradable and injectable radionuclide"seed"is a promising therapeutic alternative to bracht 清华大学学术报告二:High- field functional magnetic resonance imaging and optical controls in non-human primates: implications for human brain-machine interfaces 时间:6月12日下午3:00中国科学院 苏州生物医学工程技术研究所人事教育处 《人才快讯》2012 年第三期 7 “海外人才走进科学院活动周”同时启动,来自美国、德国、英国、法国、澳大利亚、日 本等国家的 46 位获国家优秀自费留学生奖学金的海外人才代表应邀访问中国科学院,并与 国内优秀青年人才进行了交流座谈。 中科院副院长詹文龙介绍,“海外人才走进科学院活动周”旨在通过邀请海外优秀青年科 技人才集中访问中科院的有关研究所并进行学术交流,与海外人才建立起交流密切的联络机 制,向海外人才宣传国家和院的人才政策与举措,搭建长期合作与双向选择的平台。 中科院人才发展主题活动日上还举行了中国科学院“海外评审专家”聘请仪式。一批优秀人才 分别获得中科院青年科学家奖、卢嘉锡青年人才奖、中科院技术能手荣誉称号。 高校动态 清华大学学术报告一:In situ self-assembly of highly potent, biodegradable, radionuclide seeds for brachytherapy 时间:6 月 13 日下午 3:30 地点:清华大学医学科学楼 B321 报告人:Wenge Liu, Ph.D. (Associate Research Professor, Duke University) 报告摘要 Intratumoral administration of radionuclides (radionuclide therapy) has the potential to deliver the maximum amount of radioactivity to the tumor and can spare surrounding tissues from harmful side effects. All the radionuclides, however, are unable to capitalize on this effect because they are rapidly cleared from the tumor following injection due to their low molecular weight. Elastin-like polypeptides (ELP) are a class of genetically engineered polymers that undergo an inverse temperature phase transition; they are soluble at the temperatures below their characteristic transition temperature (Tt), and form insoluble aggregates above their Tt. Using this ELP, we developed a versatile, genetically engineered peptide polymer as a “smart” radionuclide carrier that displays potent antitumor efficacy by rationally tailoring intratumoral retention time through the modulation of its phase transition behavior. The therapeutic efficacy herein reported, which led to 100% response rates in two human tumor xenograft models and greater than 67% of complete tumor regression until the completion of the experiment (i.e., 60 days), is in stark contrast with the efficacy observed on our seminal work with radiolabeled ELPs. This radiotherapy modality showed very minimal systemic toxicity in mice. These data indicate the in situ self-assembly of biodegradable and injectable radionuclide “seed” is a promising therapeutic alternative to conventional brachytherapy. 清 华 大 学 学 术 报 告 二 :High-field functional magnetic resonance imaging and optical controls in non-human primates: implications for human brain-machine interfaces 时间:6 月 12 日下午 3:00
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