Ends of heptamers identify coding ends 24.5 Recombination between V and c gene segments 12 bp spacer 23 bp spacer generates deletions and rearrangements Cleavage Signal end[Signal end oding encoding end> J-C Figure 24.13 Breakage and reunion at consensus Joining sequences generates V.J-C Immunoglobulin genes Coding joint ignal joint 消当Figure 24.13 Breakage and reunion at consensus sequences generates immunoglobulin genes. 24.5 Recombination between V and C gene segments generates deletions and rearrangements