Linkage Analysis Neurofibroma, NFl RFLP Ⅲ 2345678 ECoR I ECOR I ECoR I 3.0kb 1.7 kb ProbeLinkage Analysis EcoRⅠ EcoRⅠ EcoRⅠ 3.0 kb 1.7 kb Probe Neurofibroma, NF1 RFLP Ⅰ Ⅱ Ⅲ 1 2 1 2 3 4 5 6 7 8 1 2 3 4 5 6 7 8