A. Androgens and antiandrogens Contraindications 1. pregnant women, infants and young children (somatotropin is more appropriate to produce a growth spurt) 2. male patients with carcinoma of the prostate or breast. 3. renal or cardiac disease predisposed to edema Caution: Several cases of hepatocellular carcinoma have been reported in patients with aplastic anemia treated with androgen anabolic therapy. Erythropoietin and colony- stimulating factors should be used insteadA. Androgens and antiandrogens Contraindications 1. pregnant women, infants and young children (somatotropin is more appropriate to produce a growth spurt). 2. male patients with carcinoma of the prostate or breast. 3. renal or cardiac disease predisposed to edema Caution: Several cases of hepatocellular carcinoma have been reported in patients with aplastic anemia treated with androgen anabolic therapy. Erythropoietin and colony￾stimulating factors should be used instead