o A nucleophile is a reagent that seeks a positive center. This is the positive The electronegative center that the halogen polarizes nucleophile seeks. the C-X bond o A nucleophile is any negative ion or any neutral molecule that has at least one unshared electron pair. HO: CHO:HS:CH3S CH3NH CN :I H,0 CH,OH CH3SH CH3NH2 College of Science