复旦大学：《细胞与医学遗传学实验》教学课件_实验（三）细胞损伤与保护——凋亡相关基因－Bax 在不同细胞中表达产物差异检测

1.Genes can be mutated in many ways 2. Somatic versus germline mutations 3. Types of mutation effects

1. What is gene therapy? 2. How does gene therapy work? 3. The current status of gene therapy research 4. Factors kept gene therapy effective 5. Some recent developments 6. Some of the ethical considerations

1. Gene Chemistry 2. Gene Structure 3. DNA replication 4. Gene Expression

1.Genes can be mutated in many ways 2. Somatic versus germline mutations 3. Types of mutation effects

1. Pedigree and Proband 2. autosomal dominant inheritance 3. AUTOSOMAL RECESSIVE INHERITANCE 4. X-LINKED DOMINANT INHERITANCE 5. X-LINKED RECESSIVE INHERITANCE 6. Y-linked 7. SPECIAL FEATURES

掌握细胞分化的一般概念，理解细胞的分化潜能的分类，掌握细胞分化和基因表达关系，调控和影响细胞分化的因素，了解细胞分化与恶性变关系

1. Variability and Gene (or Allelic) Frequencies 2. The Hardy-Weinberg Law 3. Factors that Affect Stability of Gene Frequencies

2. Inborn Errors of Metabolism Inborn errors of metabolism are rare genetic disorders in which the body cannot turn food into energy (metabolize food) normally. The disorders are usually caused by defects in the enzymes involved in the biochemical pathways that break down food components

1. What is gene therapy? 2. How does gene therapy work? 3. The current status of gene therapy research 4. Factors kept gene therapy effective 5. Some recent developments 6. Some of the ethical considerations