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They are solid, thinner filament structures (6-8 nm, in diameter) composed of a double-helical polymer of the protein actin. And microfilaments play a key role of in virtually all types of contractility and location of cells as well as motility within cells
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5.1 Introduction Non-migratory bioactive polymers (NMBP)are a class of polymers that possess biological activity without the active components migrating from the polymer to the substrate. This concept has existed for some time (Bachler et al., 1970; Brody and Budny, 1995; Katchalski-Katzir 1993) and has been applied primarily to immobilised enzyme
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Polymer Properties Depend On 1. What elements are in the molecule? 2. What size(molecular weight) is the molecule? 3. Is the molecule polar or non-polar? 4. What shape is the molecule? 5. What is its thermal history? 6. What is its mechanical history?
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1. Re-derive the equation for equilibrium swelling of a polyelectrolyte gel where the polymer chains contain a basic ionizable group that becomes positively charged with decreasing pH
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1. Re-derive the equation for equilibrium swelling of a polyelectrolyte gel where the polymer chains contain a basic ionizable group that becomes positively charged with decreasing pH
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1. An early study in the development of peptide-presenting biomaterials showed that polymer surfaces bearing RGD peptides at a density equivalent to -10 peptides per each cell was sufficient to promote cell attachment, spreading and subsequent cell growth. In contrast, when whole
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Biodegradable Solid Polymers Spring 2003 Issued Day 1 5 points/problem(20 points total) 1. The chemical structure of a new degradable polymer, poly(ethylene glycol)-b-polylysine-b- poly (D, L-lactide), is shown below a. Based on chemical structure al
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Biodegradable Solid Polymers Spring 2003 Issued Day 1 Day 3 1. The chemical structure of a new degradable polymer, poly (ethylene glycol)-b-polylysine-b- poly (D, L-lactide)
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Lecture 5: Controlled Release Devices Last time: Using enzyme substrate and cytokine peptides to engineer biological recognition of synthetic polymers Today: principles of controlled release devices based on degradable polymers Synthesis of controlled release devices Theory of polymer-based controlled release
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Lecture 2: Molecular Design and Synthesis of Biomaterials I: Biodegradable Solid Polymeric Materials(continued) hemistry and physical chemistry of degrading polymeric solids for biomaterials Today Theory of polymer erosion Enzymatic degradation of synthetic biomaterials Designing degradable materials Reading
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