B. Cell-Matrix Interactions A. How cells pull onto and deform the matrix to which they attach themselves. B. Cell-matrix interactions control the spontaneous closure of wounds in organs. C. What happens when regeneration is induced?

CELLS FOR TISSUE ENGINEERING/REGENERATIVE MEDICINE Autologous -Differentiated parenchymal cells of same or other tissue type -Stem cells (adult) Allogeneic

SACHUSE Massachusetts Institute of Technology Harvard Medical School Brigham and Women's/Massachusetts General Hosp

biologically active model of ECM acts as an insoluble regulator of cell function image removed due to copyright considerations

Outline of three lectures on Irreversible Healing of Extracellular Matrix. A. Irreversible healing of ECMs in different organs. B. Structure and function of naturally occurring ECMs. C. Synthesis of biologically active ECM models

Introduction. Chapter 1. Irreversible Healing of Extracellular Matrix. Chapter 2. Cell-Matrix Interactions. Chapter 3. Synthesis of Tissues and Organs. TEXT: I. V. Yannas. Tissue and Organ Regeneration in Adults. New York: Springer, 2001

PROTACS: CHIMERIC MOLECULES TO TARGET PROTEINS FOR UBIQUITINATION AND (taken from KM Sakamoto, Mol. Genetics and Metabolism 77(2002)44-56) target targettargettarget target target target target target To circumvent the problem of transducing cells at

The principle of Maximum Conformality(PMC) Some applications Summary and Outlook

Piecewise Linear interpolation Piecewise Cubic Hermite Interpolation Cubic splines

Chapter 6 Linear systems Triangular Problems Banded Problems Full Problems Analysis