定义:气管、支气管粘膜及其周围组织的慢性 非特异性炎症。临床特征,咳嗽、咳痰或伴 有喘息及反复发作的慢性过程。病情缓慢进 展,常并发阻塞性肺气肿,甚至肺动脉高压 肺源性心脏病

一、海平面、静息、呼吸空气 或伴PaCO2>50mmg(6.67kpa) 二、排除 心内解剖分流 心排出量↓↓

医院是对群众或特定人群进行防病、治病的场所,备有一定数量的病床、必要的设施 和具有救死扶伤精神、精湛的医学知识和技能的医务人员,以达到对门诊或住院患者实施 科学的诊疗、护理为目的的医疗机构

Medical Genetics Genes are entities that parents pass to offspring during reproduction

The most common gene change involves a single base mismatch--a misspelling--placing the wrong base in the DNA. At other times, a single base may be dropped or added. And sometimes large pieces of DNA are mistakenly repeated or deleted

一、前言 二、数量性状的多基因遗传 三、多基因病的遗传

single-gene disorder or monogenic disorder Some disorders result when a mutation causes the product of a single gene to be altered or missing. These disorders are inherited in simple patterns similar to or identical with those described by Mendel for certain discrete characteristics in garden peas. Therefore it's also called mendelian diseases

一、前言 二、系谱与系谱分析法 三、常染色体显性遗传病的遗传 四、常染色体隐性遗传病的遗传 五、X连锁显性遗传病的遗传 六、X连锁隐性遗传病的遗传Y连锁遗传病的遗传 七、影响单基因遗传病分析的因素

一、前言 二、基因突变导致蛋白功能改变 三、基因突变引起性状改变的机制

Medical Genetics Gene Mutation Change in genes caused by change in structure of the dna