公共关系传播是指社会组织利用各种媒介,有计划地将信息或观点与公众进行交流沟通以达到争取公众、信息共享的目的。 （1)传播是一个有计划的完整的行动过程。 （2)传播是一种信息的分享活动

建模和分析（I） 通用的建模问题、建模目的、组织和非功能需求

The Cell and Its Membrane Molecules Plasma membrane-5nm Rough ER Smooth ER Nucleus-3-10 um Nucleolus Nuclear pore -Golgi complex Extracellular

BIOMATERIALS-TISSUE INTERACTIONS: \Tools\ for Understanding the Molecular, Cellular, and Physiological, Bases of the Tissue Response to Implants M. Spector, Ph. D. and I. V. Yannas, Ph.D. BIOMATERIALS-TISSUE INTERACTIONS

UNIT CELL PROCESSES Regulator UCP Cell Matrix Product Regulator Connect. ECM Mitosis Tiss. Adhesion Sy Synthesis Epithelia |Protein Migration Muscle Collagen

RESPONSE TO IMPLANTS WOUND HEALING flury Vascular Response Inflammation Tissue of labile Tissue of and stable cells Permanent cells Framework framework Scar Intact Destroyed

RESPONSE TO IMPLANTS: WOUND HEALING Surgical Implantation Inc. time Vascular Response Acute Clotting Inflammation Phagocytosis Granulation Neovascularization New Collagen Synthesis Tissue

C. Synthesis of biologically active scaffolds (regeneration templates) 1. History of biologically active scaffolds (regeneration templates). 2. Physical chemistry of collagen: Melting of collagen quaternary structure (thromboresistance). Melting of collagen tertiary structure (gelatinization). 3. Synthesis of ECM analogs: lonic complexation

TISSUE ENGINEERING What is tissue engineering Production of tissue in vitro by growing cells in porous, absorbable scaffolds (matrices). Why is tissue engineering necessary? Most tissues cannot regenerate when injured or diseased

UNIT CELL PROCESSES Concept of a \Control Volume\ around a Cell Soluble Regulator Cell Matrix