Lecture 10: Bioengineering applications of hydrogels: Molecular Imprinting and Drug Delivery Last Day polyelectrolyte gels Polyelectrolyte complexes and multilayers Applications in bioengineering Theory of ionic gel swelling Toda Molecular imprinting

Lecture 7: Hydrogel Biomaterials: Structure and Physical Chemistry Last Day: programmed/regulated/multifactor controlled release for drug delivery and tissue engineering

Lecture 5: Controlled Release Devices Last time: Using enzyme substrate and cytokine peptides to engineer biological recognition of synthetic polymers Today: principles of controlled release devices based on degradable polymers Synthesis of controlled release devices Theory of polymer-based controlled release

Molecular Principles of Biomaterials Spring 2003 Lecture 2: Molecular Design and Synthesis of Biomaterials I: Biodegradable Materials Chemistry of Biodegradable Materials Hydrolytically degraded biomaterials Common hydrolytically unstable linkages Ester

Lecture 2: Molecular Design and Synthesis of Biomaterials I: Biodegradable Solid Polymeric Materials(continued) hemistry and physical chemistry of degrading polymeric solids for biomaterials Today Theory of polymer erosion Enzymatic degradation of synthetic biomaterials Designing degradable materials Reading

Biodegradable solid polymeric Materials Today course overview and administrative details Intro to concepts covered Chemistry and physical chemistry of biodegradable polymeric solids Hand-outs course syllabus Course administrative details Readin Third-Generation Biomedical Materials. \LL Hench and j M. Polak. Science 295

醛、酮和醌的分子结构中都含有羰基(图.11.1), 总称为羰基化合物。羰基至少和一个氢原子结合的化 合物叫醛(-CHO又叫醛基,图11.2),羰基和两个烃基 结合的化合物叫酮。醌是一类不饱和环二酮,在分子 中含有两个双键和两个羰基。例如,图11.3 羰基是醛、酮的官能团

一、原子结构(ppt第1章,《结构和物性》第1章) 二、分子结构(含配合物) (ppt第2,6,7章,《结构和物性》第2,4章) 三、晶体结构(晶胞,点阵)(ppt第9章,《结构和物性》第8章)

药物的第相生物转化是指体内各种酶对药物分子进行的官能团化反应,主要发生在药物分子的 官能团上,或分子结构中活性较高、位阻较小的部位,包括引入新的官能团及改变原有的官能团。本 节讲授的主要内容包括氧化反应、还原反应、脱卤素反应和水解反应

木材是天然高分子有机体,和低分子物质组 成。构成木材细胞壁( cell wall)的主要物 质是由纤维素( cellulose)、半纤维素 ( hemicellulose)、木素( lignin)等组成, 这三种物质的分子结构和性质以及它们之间 的关系,决定了木材的各种性质,并且对木 材的加工工艺和木材产品的特性有很大影响。 例如:三者都有OH( hydroxyl),这就 决定了木材具有吸湿性,木材在大气中会失 水干缩和吸湿膨胀,产生了木材体积不稳定 性。另外在胶合过程、涂饰过程中,化学处 理有滞火、防腐、改性、制浆等都涉及到许 多木材化学方面的知识