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Thus far have considered separately beam - takes bending loads column -takes axial loads Now combine the two and look at the beam-column (Note: same geometrical restrictions as on others
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We have looked at basic in-plane loading. Lets now consider a second\building block of types of loading: basic torsion There are 3 basic types of behavior depending on the type of cross-section
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Thus far we have discussed mechanical loading and the stresses and strains caused by that We noted, however, that the environment can have an effect on the behavior of materials and structures. Let's first consider:
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There are many structural configurations where we do not have to deal with the full 3-D case. First let's consider the models Let's then see under what conditions we can apply them A. Plane Stress
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We do not characterize materials by their E mnpq The Emnpa are useful in doing transformations, manipulations, etc. We characterize materials by their \ENGINEERING CONSTANTS\ (or, Elastic Constants)
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Let's first review a bit... from Unified, saw that there are basic considerations in elasticity: 1. Equilibrium 2. Strain-Displacement 3. Stress- Strain Relations (Constitutive Relations)
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Introduction to Manufacturing a Manufacturing is the physica/ realization of the previously designed parts Metrics to assess the\ performance\of mfg Quality does it meet specifications?
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Alternative views on gradient sensing Postma and van hastert. 'a diffusion-translocation model for gradient sensing by chemotactic cells Biophys.J.81,1314(2001) Levchenko and Iglesias. Models of eukaryotic gradient sensing: applications to chemotaxis of amoeba and neutrophils
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Review Turing-Gierer-Meinhardt models Local excitation, global inhibition 22r+hq
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L14: 14 Lectures past and 1 1 to go Part 'The cell as a well-stirred bioreactor topICs Lambda phage lysis-lysogeny switch Synthetic genetic switch Switches as memory storage Chemotaxis: perfect adaptation or not? Synthetic genetic oscillators
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