慢性肉芽肿性疾病 (chronic guanulomatous diseasse) 一、X连锁/常染色体隐性遗传性疾病 二、 NADPH氧化酶缺乏 三、过氧化氢酶阳性菌感染

ANTITHROMBOTIC PROPERTIES Inhibition of platelet aggregation: PGL NO, ADPase Anticoagulant -binding and inhibition of thrombin: Antithrombin acceleration by heparin-like molecules, thrombomodulin activation of protein C/S, a2-macroglobulin. Fibrinlysis: Tissue plasminogen activator (tPA)

Motional pathway of embolus: Embolus from left heart cavity or arterial system Embolus from right heart cavity or venous system Embolus from portal veins Paradoxical embolism Retrograde ethrombus

CELLULAR ADAPTATION Excessive physiologic stresses. Some pathologic stimuli. A new, but altered state preserving the viability of the cell

Definition of pathology Pathology is to study diseases by scientific methods. Disease may be defined as an abnormal alteration of structure or function in any part of the body

FATTY CHANGE Excessive entry of free fatty acids into the liver (starvation, corticosteroid therapy). Enhanced fatty acid synthesis. Decreased fatty acid oxidation. Increased esterification of fatty acid to triglycerides (alcohol). Decreased apoprotein synthesis (CCl). Impaired lipoprotein secretion from the liver (alcohol)

1、掌握取材的定义及注意事项; 2、掌握常用固定液的配制 3、掌握组织检材制片前的处理和准备; 4、掌握组织脱水、透明的过程及注意事项; 5、熟悉切片机的操作;

1、死因分析的意义 2、死因分类 3、死因分析的步骤 4.死因分析中较难解决的问题

1、掌握现场尸体外表检验方法; 2、掌握法医解剖程序、方法; 3、掌握脏器检验方法及检材的采取方法; 4、熟悉特殊尸体检查方法; 5、了解组织切片染色方法及程序

1、了解气压等因素对人体造成的损害和致死机理,出事现场及尸体的形态学特点。 2、三种气压、电离辐射、激光、微波及高频的物理性质,三种激光、微波及高频对人体的损害及其后果; 3、理解气压等物理因素对机体损害的机理或生物学效应;