HIV是一双股单链RNA病毒，属逆转录病毒科，慢病毒亚科。分为两型。即HIV－1和HIV－2。目前世界范围内流行目前世界范围内流行的主要由HIV－1所致。HIV－2仅在西非部分地区流行。HIV对热敏感，56℃30分钟、25%以上乙醇、0.2%次氯酸钠、1%戊二醛等处理后戊二醛等处理后均可灭活。但对0.1%福尔马林、电离辐射和紫外线等的抵抗力较强

1 ANTI-INFECTIVE THERAPY 2 SEPSIS SYNDROME 3 THE FEBRILE PATIENT 4 PULMONARY INFECTIONS 5 MEASLES (RUBEOLA) 6 CENTRAL NERVOUS SYSTOM INFECTIONS 7 MUMPS 8 GASTROINTESTINAL AND HEPATOBILIARY INFECTIONS 9 SCARLET FEVER 10 STREPTOCOCCUS PYOGENES (GROUP A STREPTOCOCCUS) 11 DIPHTHERIA (CORYNEBACTERIUM DIPHTHERIAE) 12 PARASITIC INFECTIONS 13 ZOONOTIC INFECTIONS 14 BIOTERRORISM 15 SERIOUS VIRAL ILLNESS IN THE ADULT PATIENT 16 PERTUSSIS (BORDETELLA PERTUSSIS AND BORDETELLA 17 HIV INFECTION 18 VARICELLA (CHICKENPOX) 19 TYPHOID FEVER

1 ANTI-INFECTIVE THERAPY 1 2 THE SEPSIS SYNDROME 57 3 THE FEBRILE PATIENT 66 4 PULMONARY INFECTIONS 79 5 EYE, EAR NOSE, AND THROAT INFECTIONS 120 6 CENTRAL NERVOUS SYSTEM INFECTIONS 139 7 CARDIOVASCULAR INFECTIONS 167 8 GASTROINTESTINAL AND HEPATOBILIARY INFECTIONS 190 9 GENITOURINARY TRACT INFECTIONS AND SEXUALLY TRANSMITTED DISEASES (STDs) 231 10 SKIN AND SOFT TISSUE INFECTIONS 256 11 BONE AND JOINT INFECTIONS 273 12 PARASITIC INFECTIONS 288 13 ZOONOTIC INFECTIONS 322 14 BIOTERRORISM 349 15 SERIOUS ADULT VIRAL ILLNESSES OTHER THAN HIV 365 16 INFECTIONS IN THE IMMUNOCOMPROMISED HOST 384 17 HIV INFECTION 397

It is term used as a convenient description for all phases of the disease caused by a bacteria called Brucella. Many names have been applied to it as: 1. Malta fever 2. Mediterranean fever. 3. Gibraltar or rock fever 4. Undulant fever

一、发热的定义、机制、类型 二、发热查因的概念、病因、特点 三、发热查因的诊断思路 四、临床实例 五、疑难感染病（发热）诊疗中心

1 常用抗生素特点及应用 2 抗生素不良反应 3 抗生素临床使用原则 4 常见感染性疾病及治疗

由疟原虫所致、主要经按蚊叮咬而传播 、主要经按蚊叮咬而传播 在肝细胞内寄生、繁殖，成熟后侵入红 ，成熟后侵入红细胞，使红细胞成批破裂而致病 ，使红细胞成批破裂而致病 临床特征为间歇性寒战、高热、大汗常伴有肝、脾肿大及贫血 间日疟和卵形疟常有复发 恶性疟发热不规则，常侵犯内脏，可出现脑型疟等凶险发作

血吸虫病（schistosomiasis)是由血吸虫寄生在人体静脉系统所引起的寄生虫病。 主要病变是由虫卵引起肝与肠的肉芽肿。 急性期有发热、肝肿大和压痛、腹痛、腹泻、血便，血中嗜酸性粒细胞显著增多。 慢性期以肝脾肿大为主， 晚期以肝脏门静脉周围纤维化为主，可发展为门静脉高压症(食道、胃底静脉曲张、巨脾与腹水)

• Viral hepatitis is a group systemic infection affecting the liver predominantly caused by 5 kinds of viruses at least • Five hepatotropic hepatitis viruses are responsible for the vast majority of hepatitis cases(classical) : Hepatitis A virus (HAV) Hepatitis B virus (HBV) Hepatitis C virus (HCV) Hepatitis D or delta virus (HDV) Hepatitis E virus (HEV)

• 出血热肾综合征（Hemorrhagic fever with renal syndroms, HFRS)，由病毒引起的、经鼠传播的一 种自然疫源性疾病。 • 病理特征： 全身小血管和毛细血管广泛损伤。 • 临床特征： 发热，低血压，出血，肾损害