Introduction Diabetes mellitus is a heterogeneous group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both

Introduction Growth and growth disorders Adrenal disorders and sexual development abnormalities Thvroid disorders Disorders of calcium and phosphorus metabolism Diabetes mellitus and hypoglycemia Other disorders: obesity, autoimune endocrinopathies, tumor, inborn metabolic

Introduction Growth and growth disorders Adrenal disorders and sexual development abnormalities Thyroid disorders Disorders of calcium and phosphorus metabolism Diabetes mellitus and hypoglycemia Other disorders: obesity, autoimune

DISCOVERy OF THE ROLE OF UBIQUITIN IN PROTEIN DEGRADATION HISTORICAL FACTS Courtesy of Sam Griffiths-Jones. Used with permission Source: \Peptide models for protein beta-sheets hD thesis, University of Nottingham, 2001 8(1975)Ubiquitin was first isolated by Gideon Goldstein and colleagues from the thymus(reason why it was originally thought to be a thymic hormone)

PROTACS: CHIMERIC MOLECULES TO TARGET PROTEINS FOR UBIQUITINATION AND (taken from KM Sakamoto, Mol. Genetics and Metabolism 77(2002)44-56) target targettargettarget target target target target target To circumvent the problem of transducing cells at

Propagation: lonospheric delay Summary -Quick review/introduction to propagating waves -Effects of low density plasma Additional effects -Treatment of ionospheric delay in GPS processing -Examples of some results

第一章 生产与运作管理概述 Introduction to the Production and Operations 第二章 质量管理 Quality Management 第三章 项目管理 Project Management 第四章 产品与过程设计 Design of Product and Process 第五章 设施与作业设计 Design of Facilities and Jobs 第六章 生产能力与计划 Capacity and Planning 第七章 独立需求系统 Systems for Independent Demand 第八章 相关需求管理 Management for Dependent Demand 第九章 进度计划和控制 Scheduling and Control 第十章 新型生产系统 New Production Systems

Introduction A primary goal of your efforts in this course will be to gather empirical data so as to prove(or disprove) your hypothesis Typically the data that you gather will not directly satisfy this goal Rather, it will be necessary to \reduce\the data. to put it into an appropriate form, so that you can

1. Introduction 2.Pre-reading 3. Writing skills

Lesson 1: Introduction to Accounting Learning Objectives Understand the concepts of economic man and nature of firm from the perspective of economic man 2. Appreciate the trust issue and the unique role of accounting in trust building and maintaining